Details for gene set NCI_P38 MAPK SIGNALING PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos
Phenotype	phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos
Upregulated in class	BT_ATM_minus
GeneSet	NCI_P38 MAPK SIGNALING PATHWAY
Enrichment Score (ES)	-0.43934876
Normalized Enrichment Score (NES)	-1.8348204
Nominal p-value	0.0
FDR q-value	0.06071174
FWER p-Value	0.524

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CEBPB	1418901_at 1427844_a_at	129	5.556	0.0136	No
2	LCK	1425396_a_at 1439145_at 1439146_s_at 1457917_at	361	4.302	0.0181	No
3	BLK	1422775_at	548	3.786	0.0229	No
4	MAP3K12	1417115_at 1438908_at 1456565_s_at	732	3.365	0.0263	No
5	GATA3	1448886_at	849	3.181	0.0321	No
6	KPNB1	1416925_at 1434357_a_at 1448526_at 1451967_x_at	885	3.122	0.0415	No
7	MAP3K7	1419988_at 1425795_a_at 1426627_at 1449693_at 1455441_at 1458787_at	1041	2.954	0.0447	No
8	ETV1	1422607_at 1445314_at 1450684_at	1054	2.944	0.0545	No
9	CDK4	1422441_x_at	1289	2.691	0.0532	No
10	MAP3K6	1449901_a_at	1729	2.313	0.0412	No
11	RPS6KA5	1431050_at 1437625_at 1439004_at 1440343_at	1779	2.279	0.0470	No
12	IL2RA	1420691_at 1420692_at	2105	2.077	0.0393	No
13	PPARG	1420715_a_at	2109	2.076	0.0465	No
14	SFN	1448612_at	2270	1.991	0.0461	No
15	ATF1	1417296_at	2436	1.925	0.0453	No
16	SLC3A2	1425364_a_at	2461	1.913	0.0509	No
17	HSPB1	1422943_a_at 1425964_x_at 1427853_a_at 1427854_x_at 1453914_at	2799	1.788	0.0417	No
18	FGR	1419526_at 1442804_at	2992	1.723	0.0390	No
19	XPO1	1418442_at 1418443_at 1448070_at	3062	1.704	0.0418	No
20	RAC1	1423734_at 1437674_at 1451086_s_at	3186	1.669	0.0420	No
21	EIF4EBP1	1417562_at 1417563_at 1434976_x_at	3405	1.597	0.0376	No
22	YES1	1418470_at 1449090_a_at 1456843_at 1458878_at	4228	1.358	0.0046	No
23	SNTA1	1416825_at	4587	1.262	-0.0074	No
24	PPARGC1A	1434099_at 1434100_x_at 1437751_at 1456395_at 1460336_at	4822	1.203	-0.0139	No
25	YWHAG	1420816_at 1420817_at 1450012_x_at 1459693_x_at	4979	1.167	-0.0170	No
26	IFNG	1425947_at	5016	1.158	-0.0146	No
27	MEF2D	1421388_at 1434487_at 1436642_x_at 1437300_at 1458901_at	5091	1.143	-0.0139	No
28	TNF	1419607_at	5329	1.099	-0.0210	No
29	MAP3K7IP1	1426898_at 1447692_x_at	5350	1.096	-0.0180	No
30	CCND1	1417419_at 1417420_at 1448698_at	5473	1.073	-0.0199	No
31	RNF128	1418318_at 1449036_at	5517	1.062	-0.0181	No
32	MAPK13	1448871_at	5732	1.020	-0.0244	No
33	RAN	1443131_at 1446819_at 1447478_at 1460551_at	5840	1.003	-0.0258	No
34	MAP3K10	1436373_at 1440500_at 1457456_at 1458651_at	5899	0.992	-0.0249	No
35	RALA	1423137_at 1450870_at 1456049_at	5923	0.987	-0.0225	No
36	DUSP8	1418714_at	5934	0.985	-0.0195	No
37	CREBBP	1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at	5999	0.972	-0.0190	No
38	YWHAB	1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at	6409	0.903	-0.0347	No
39	MAPKAPK2	1426648_at	6416	0.901	-0.0318	No
40	PKN1	1458674_at 1459231_at	6638	0.860	-0.0389	No
41	BAD	1416582_a_at 1416583_at	6794	0.832	-0.0431	No
42	CALM2	1422414_a_at 1423807_a_at	6811	0.830	-0.0409	No
43	IL3	1450566_at	7020	0.793	-0.0477	No
44	HCK	1446553_at 1449455_at	7239	0.756	-0.0550	No
45	IRF4	1421173_at 1421174_at	7367	0.736	-0.0583	No
46	GADD45G	1453851_a_at	7540	0.708	-0.0637	No
47	AKAP5	1447301_at	7675	0.687	-0.0674	No
48	ELK4	1422233_at 1427162_a_at 1447571_at 1450549_s_at	7690	0.684	-0.0657	No
49	ESR1	1421244_at 1435663_at 1457877_at 1460591_at	7977	0.634	-0.0766	No
50	MAPK12	1447823_x_at 1449283_a_at	7998	0.632	-0.0753	No
51	MAPKAPK5	1417016_at 1439828_at	8180	0.604	-0.0815	No
52	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	8221	0.595	-0.0812	No
53	EEF2K	1437829_s_at 1439860_at 1449013_at	8338	0.580	-0.0845	No
54	PRKG1	1443663_at 1443811_at 1443812_x_at 1444232_at 1445807_at 1445998_at 1449876_at	8418	0.567	-0.0861	No
55	PRKCZ	1418085_at 1449692_at 1454902_at	8443	0.563	-0.0853	No
56	PAK3	1417923_at 1417924_at 1437318_at	8795	0.506	-0.0996	No
57	DUSP16	1418401_a_at 1440615_at 1440651_at	8941	0.482	-0.1046	No
58	EGR4	1449977_at	9046	0.466	-0.1077	No
59	PTPRK	1423277_at 1423278_at 1431680_a_at 1441276_at 1441277_s_at 1441644_at 1443491_at 1443699_at 1444763_at	9250	0.435	-0.1155	No
60	SRF	1418255_s_at 1418256_at	9309	0.428	-0.1167	No
61	CD40LG	1422283_at	9546	0.393	-0.1261	No
62	PIM1	1423006_at 1435458_at	9576	0.389	-0.1261	No
63	MITF	1422025_at 1455214_at	9587	0.387	-0.1252	No
64	MAPK14	1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at	9589	0.387	-0.1239	No
65	CASP3	1426165_a_at 1430192_at 1449839_at	9681	0.373	-0.1268	No
66	PAK2	1434250_at 1454887_at	9770	0.356	-0.1295	No
67	PTGS2	1417262_at 1417263_at	9972	0.326	-0.1376	No
68	IL5	1425546_a_at 1442049_at 1450550_at	10259	0.282	-0.1498	No
69	BCL2	1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at	10517	0.241	-0.1607	No
70	PRKCD	1422847_a_at 1442256_at	10621	0.228	-0.1647	No
71	FASLG	1418803_a_at 1449235_at	10638	0.224	-0.1646	No
72	TP53	1426538_a_at 1427739_a_at 1438808_at 1457623_x_at 1459780_at 1459781_x_at	10770	0.205	-0.1699	No
73	PLA2G4A	1448558_a_at	11256	0.131	-0.1917	No
74	TH	1420546_at	11369	0.113	-0.1965	No
75	TCF3	1436207_at 1450117_at	11407	0.108	-0.1978	No
76	TRAF6	1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at	11435	0.105	-0.1987	No
77	PTPN1	1417068_a_at 1438670_at	11489	0.096	-0.2008	No
78	NFATC2	1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at	11878	0.033	-0.2185	No
79	MAPK9	1421876_at 1421877_at 1421878_at	12075	0.004	-0.2275	No
80	MAPK11	1421925_at 1421926_at	12080	0.003	-0.2276	No
81	HBP1	1432143_a_at 1438430_at 1446269_at 1460367_at	12083	0.003	-0.2277	No
82	EIF4E	1450909_at 1457489_at 1459371_at	12117	-0.004	-0.2292	No
83	YWHAE	1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at	12203	-0.016	-0.2331	No
84	RIPK1	1419508_at 1439273_at 1449485_at	12208	-0.017	-0.2332	No
85	EGR3	1421486_at 1436329_at	12466	-0.064	-0.2448	No
86	STMN1	1415849_s_at	12732	-0.110	-0.2566	No
87	ATM	1421205_at 1428830_at	12862	-0.132	-0.2620	No
88	CALM1	1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at	12917	-0.142	-0.2640	No
89	FOSL1	1417487_at 1417488_at	13244	-0.198	-0.2783	No
90	ATF2	1426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at	13267	-0.201	-0.2786	No
91	MAPKAPK3	1434815_a_at 1437494_at	13543	-0.247	-0.2903	No
92	PRKCE	1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at	13855	-0.301	-0.3036	No
93	MAF	1435828_at 1437473_at 1444073_at 1447849_s_at 1447945_at 1456060_at	13869	-0.302	-0.3031	No
94	PRKCH	1422079_at 1434248_at	13875	-0.303	-0.3023	No
95	MKNK1	1417630_at 1417631_at 1454119_at	14424	-0.404	-0.3260	No
96	CSF2	1427429_at	14633	-0.444	-0.3340	No
97	PRKACA	1447720_x_at 1450519_a_at	14981	-0.518	-0.3481	No
98	POU2F1	1419716_a_at 1427695_a_at 1427835_at	15046	-0.533	-0.3492	No
99	MAP2K3	1425456_a_at 1451714_a_at	15187	-0.559	-0.3537	No
100	MAP3K8	1419208_at	15282	-0.580	-0.3559	No
101	NUP214	1434351_at 1456503_at 1457815_at	15760	-0.682	-0.3755	No
102	MEF2C	1421027_a_at 1421028_a_at 1424852_at 1439946_at 1445420_at 1446484_at 1451506_at 1451507_at 1458551_at	15852	-0.704	-0.3772	No
103	PAK1	1420979_at 1420980_at 1450070_s_at 1459029_at	15927	-0.720	-0.3780	No
104	IL4	1449864_at	15987	-0.733	-0.3782	No
105	FOS	1423100_at	16185	-0.784	-0.3845	No
106	ITCH	1415769_at 1431316_at 1459332_at	16238	-0.796	-0.3841	No
107	MAPK8	1420931_at 1420932_at 1437045_at 1440856_at 1457936_at	16585	-0.880	-0.3969	No
108	CREB1	1421582_a_at 1421583_at 1423402_at 1428755_at 1452529_a_at 1452901_at	16714	-0.917	-0.3995	No
109	RALB	1417744_a_at 1435517_x_at	16826	-0.942	-0.4013	No
110	MAP3K7IP2	1423462_at 1451003_at	16940	-0.965	-0.4031	No
111	MEF2A	1421252_a_at 1425426_a_at 1427185_at 1427186_a_at 1452347_at	17019	-0.982	-0.4032	No
112	DUSP10	1417163_at 1417164_at	17100	-1.000	-0.4034	No
113	FKBP1A	1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at	17106	-1.000	-0.4001	No
114	YWHAZ	1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at	17139	-1.007	-0.3980	No
115	CSNK1A1	1424827_a_at 1428537_at 1430529_at 1451497_at 1456216_at	17199	-1.019	-0.3972	No
116	PRKCQ	1426044_a_at	17590	-1.113	-0.4112	No
117	YWHAH	1416004_at	17768	-1.162	-0.4152	No
118	FYN	1417558_at 1441647_at 1448765_at	17777	-1.164	-0.4115	No
119	GSK3B	1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at	17944	-1.216	-0.4149	No
120	FOXP3	1420765_a_at 1457082_at	18112	-1.270	-0.4181	No
121	ATF6	1435444_at 1453288_at 1456021_at	18185	-1.293	-0.4168	No
122	CALM3	1426710_at 1438825_at 1438826_x_at 1450864_at	18292	-1.328	-0.4170	No
123	DDIT3	1417516_at 1443897_at	18293	-1.328	-0.4124	No
124	JUN	1417409_at 1448694_at	18344	-1.347	-0.4099	No
125	SRC	1423240_at 1450918_s_at	18385	-1.363	-0.4070	No
126	SLC9A1	1417397_at	18796	-1.538	-0.4204	No
127	E2F1	1417878_at 1431875_a_at 1447840_x_at	18822	-1.547	-0.4161	No
128	EP300	1434765_at	18998	-1.622	-0.4185	No
129	RPS6KA4	1438243_at 1448498_at	19189	-1.699	-0.4212	No
130	USF1	1426164_a_at 1448805_at 1459758_at	19431	-1.814	-0.4259	No
131	MAP3K4	1421450_a_at 1447667_x_at 1450253_a_at 1459800_s_at	19710	-2.006	-0.4316	No
132	TAOK3	1435964_a_at 1444366_at 1444881_at 1447257_at 1455733_at	19879	-2.140	-0.4318	Yes
133	CTLA4	1419334_at	19997	-2.246	-0.4293	Yes
134	FKBP8	1416113_at	20126	-2.360	-0.4269	Yes
135	CAMK4	1421941_at 1426167_a_at 1439843_at 1442822_at 1452572_at	20147	-2.379	-0.4195	Yes
136	NFATC3	1419976_s_at 1452497_a_at	20174	-2.397	-0.4122	Yes
137	DGKA	1418578_at	20214	-2.428	-0.4055	Yes
138	TBX21	1449361_at	20261	-2.456	-0.3990	Yes
139	CAMK2B	1448676_at 1455869_at	20302	-2.499	-0.3920	Yes
140	GADD45A	1449519_at	20336	-2.523	-0.3847	Yes
141	MAP3K1	1424850_at	20648	-2.888	-0.3888	Yes
142	CBLB	1437304_at 1455082_at 1458469_at	20711	-2.984	-0.3812	Yes
143	RAB5A	1416426_at 1446129_at	20790	-3.088	-0.3739	Yes
144	YWHAQ	1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at	20980	-3.433	-0.3705	Yes
145	MAPK3	1427060_at	20984	-3.442	-0.3586	Yes
146	TSC2	1452105_a_at	21008	-3.475	-0.3474	Yes
147	MAP3K3	1426686_s_at 1426687_at 1436522_at	21072	-3.604	-0.3377	Yes
148	GADD45B	1420197_at 1449773_s_at 1450971_at	21203	-3.850	-0.3301	Yes
149	CSNK2A1	1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at	21262	-3.988	-0.3188	Yes
150	MAP2K4	1426233_at 1442679_at 1451982_at	21293	-4.054	-0.3059	Yes
151	TRAF2	1451233_at	21335	-4.141	-0.2932	Yes
152	GDI1	1447613_at 1451070_at	21361	-4.221	-0.2795	Yes
153	NR4A1	1416505_at	21376	-4.260	-0.2652	Yes
154	RAF1	1416078_s_at 1425419_a_at	21451	-4.510	-0.2528	Yes
155	CDC25B	1421963_a_at	21548	-4.910	-0.2399	Yes
156	MAP2K6	1426850_a_at 1459292_at	21619	-5.264	-0.2246	Yes
157	JUNB	1415899_at	21777	-6.806	-0.2079	Yes
158	EGR1	1417065_at	21803	-7.184	-0.1838	Yes
159	DUSP1	1448830_at	21821	-7.570	-0.1580	Yes
160	TAOK2	1438208_at 1443642_at 1456826_at	21829	-7.777	-0.1310	Yes
161	EGR2	1427682_a_at 1427683_at	21881	-9.155	-0.1012	Yes
162	LSP1	1417756_a_at	21884	-9.285	-0.0687	Yes
163	CCM2	1434648_a_at 1434649_at 1456290_x_at 1457339_at	21900	-9.951	-0.0344	Yes
164	NFATC1	1417621_at 1425761_a_at 1428479_at 1447084_at 1447085_s_at	21917	-10.221	0.0008	Yes